Antonio Conte will travel to Barcelona with a Chelsea squad full of players who have crossed paths with the Catalans at some point in their careers.
The obvious examples are Pedro and Cesc Fabregas, who played for the club, the first being the victim of MSN and the second failing to convince after returning home from Arsenal.
However, there are plenty of other names who have been linked to the club, such as Cesar Azpilicueta, Marcos Alonso or David Luiz, or who have denied Barcelona when playing in Spain for a rival team, like Thibaut Courtois, Alvaro Morata or Willy Caballero.
Tonight, they will all be trying to stop the Catalans again.
Thibaut Courtois knows what it takes to beat them in the Champions League, having been key to knocking them out and also securing league success with Atletico Madrid in 2014.
His deputy, Willy Caballero was suggested as a back-up for Marc-Andre ter Stegen in 2014, but the club instead opted for Claudio Bravo.
In defence, Cesar Azpilicueta has long been admired without any success in persuading him to move to Barcelona, whilst Marcos Alonso’s father was once a Blaugrana player and he too has been linked.
David Luiz was also a top target for the team, having been linked with the club several times, but he never made the move and he won’t be present for Chelsea on Wednesday.
Cesc Fabregas, like Pedro, will be returning to a ground where fans once cheered him on, though Fabregas struggled to gain the popularity of the forward.